Pediatric Immunity and Healthcare

Striving to improve the wellbeing of infants and children by deciphering the genetic and immunological causes of infantile and pediatric-onset diseases.

Pathological Jaundice

Jaundice is caused by too much bilirubin, a breakdown product of red blood cells. After being processed in the liver, bilirubin is passed out of body in poo. Newborn babies have a high number of red blood cells that are broken down and replaced frequently. Their livers are less effective...
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Biliary Atresia

Biliary Atresia (BA) affects one in every 5,000-18,000 newborns. Perinatal infection is a significant trigger, which can cause obstruction of the extrahepatic bile duct and rapid liver failure. Surgical removal of the duct remnants followed by hepatoportoenterostomy (Kasai’s procedure) is required after diagnosis. If left untreated, Biliary Atresia progression to...
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Hirschsprung's Disease

Hirschsprung's disease (HSCR) is a developmental disorder caused by the failure of enteric neural crest-derived cells (ENCC) to colonize the entire gut, leading to absence of neurons from variable lengths of the colon. Hirschsprung disease usually start in very young children, but may also occur later. The symptoms involve constipation,...
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Striving to improve the wellbeing of infants and children by deciphering the genetic and immunological causes of infantile and pediatric-onset diseases.

Pediatric Immunity & Healthcare was founded in 2021 as a research and development company. Its mission is to develop diagnosis and treatment for chronic and debilitating diseases that affect the wellbeing of infants and children. Its scientific partners and managing members are a group of passionate parents with young children, who understand the need to improve the outcomes of debilitating illnesses, even when it comes down to rare diseases that only affect a small number of children. The mechanisms and targets they discover may also benefit cancer, cardiovascular, metabolic and fibrotic diseases treatment in adults.